Programme

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Wednesday, May 17

10:00-12:45 Registration and coffee/light lunch
13:00-13:15 Introductory Remarks
John Parnavelas (London)
Session 1: Neurogenesis 1
Chair: John Parnavelas
13:15-14:00 An integrative definition of cell types during human cortical neurogenesis
Arnold Kriegstein (San Francisco)
14:00-14:45 Engineering of neurogenesis via lineage reprogramming
Benedikt Berninger (Mainz)
14:45-15:30 Cortical cell types: a deeper dive into two areas
Bosiljka Tasic (Seattle)
15:30-16:00 Coffee break
16:00-16:20 Evolutionary gain of Dbx1 expression drives subplate identity in the cerebral cortex
Alessandra Pierani (Paris)
16:20-16:40 Lack of tangentially migrating glutamatergic neurons in the developing avian brain
Fernando Garcia-Moreno (Bilbao)
16:40-17:00 An Lhx2-Ldb complex is required for early specification of the hippocampal primordium and regulation of the neuron-glia cell fate switch
Shubha Tole (Mumbai)
17:00-17:20 Mosaic analysis with double markers reveals distinct sequential functions of Lgl1 in neural stem cells
Robert Beattie (Klosterneuburg)
17:20-17:40 Regulation of cerebral cortex folding by controlling neuronal migration via FLRT adhesion molecules
Daniel del Toro (Munich)
18:00 Welcome reception

Thursday, May 18

Session 2: Neurogenesis 2
Chair: Arnold Kriegstein
9:00-10:00 The Pinckney J Harman Memorial Lecture
(Sponsored by the Cajal Club; lecture will be introduced by Christopher Walsh, the Cajal Club)
How is neurogenesis maintained for life?
Arturo Alvarez-Buylla (San Francisco)
10:00-10:45 Developmental trajectories of telencephalic GABAergic progenitors reveal canonical groundstates across all three ganglionic eminences
Gord Fishell (New York)
10:45-11:30 Dynamic layers of post-transcriptional regulation during cortical development
Debra Silver (Durham)
11:30-12:00 Coffee break
12:00-12:20 Cortical development through the lens of single cell genomics
Tomasz Nowakowski (San Francisco)
12:20-12:40 Atypical functioning of an atypical receptor: guidance of migrating interneurons by CXCR7 (ACKR3)
Ralf Stumm (Jena)
12:40-13:00 Vascular and microglial derived VegfA promote GABAergic interneuron migration in the embryonic mouse forebrain
Melissa Barber (London)
13:00-19:00 Lunch and free afternoon
Session 3: Cell Type Diversity
Chair: Zoltan Molnar
19:00-19:45 Dynamic control of neuronal diversity in the developing neocortex
Denis Jabaudon (Geneva)
19:45-20:30 Neural circuit development in the healthy and diseased human brain
Nenad Sestan (New Haven)
20:30-21:15 Cerebral cortex at single cell resolution
Steve McCarroll (Boston)
21:15-21:35 Regenerative plasticity of the epithelial structure in mammalian radial glia
Fumio Matsuzaki (Kobe)
21:35-21:55 Instructing perisomatic inhibition by direct lineage reprogramming of neocortical projection neurons
Mohammed Mostajo (Boston)

Friday, May 19

Session 4: Circuit Formation and Function
Chair: Gord Fishell
9:00-9:45 Development of electrical and chemical synapses in the thalamus
Barry Connors (Providence)
9:45-10:30 Cortical layer with no known function
Zoltan Molnar (Oxford)
10:30-11:15 Activity-dependent gating of parvalbumin interneuron function by perineuronal net proteins
Beatriz Rico (London)
11:15-11:45 Coffee break
11:45-12:05 Cell type-specific alternative splicing in developing cortical interneurons
Xavier Jaglin (New York)
12:05-12:25 Sensory inputs control cell type-specific dynamics in developing cortical networks
Natalia De Marco (New York)
12:25:12:45 Subtype-specific growth cone control over cortical circuit development, diversity, precision, and potentially regeneration through ~autonomous local RNA and protein machinery: subcellular RNA-proteome mapping
Jeffrey Macklis (Boston)
12:45-13:05 Dynamic 3D chromatin networks contribute to cell fate decisions in cortical development
Boyan Bonev (Montpellier)
13:15-15:00 Lunch
15:00-18:00 Posters 1 (P1-P60)
Free Evening

Saturday, May 20

Session 5: Developmental Disorders
Chair: Arturo Alvarez-Buylla
9:00-9:45 Somatic mutation and genomic diversity in the human cerebral cortex
Christopher Walsh (Boston)
9:45-10:30 New insights about Primary Microcephaly from Zika virus: in vitro and in vivo studies
Patricia Garcez (Rio de Janeiro)
10:30-10:50 Molecular mechanisms of primary microcephaly
Angeliki Louvi (New Haven)
10:50-11:10 Jointly reduced inhibition and excitation underlies cortical circuit-wide defects in Rett syndrome
Abhishek Banerjee (Zurich)
11:10-11:45 Coffee break
11:45-12:05 Replication stress-related microcephaly is observed upon Geminin deletion during early telencephalic formation
Argiro Kalogeropoulou (Patras)
12:05-12:25 Radial migration, form, and function of pyramidal neurons in the somatosensory cortex: effects of ethanol exposure in utero
Laurie Delatour (Dartmouth)
12:25-12:45 Novel mutations in TBCD associated with Secondary Microcephaly
Julian Heng (Perth)
13:00-15:00 Lunch
15:00-18:00 Posters 2 (P61-P125)
20:30-late Conference dinner
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